The efficacy of serratus anterior plane block with different dose of dexmedetomidine

The efficacy of serratus anterior plane block with different dose of dexmedetomidine for patients with tube thoracostomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230213057405N1

Enrollment

Registered

2023-03-14

Start date

2023-04-21

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain in patients with tube thoracostomy.

Interventions

Intervention 1: Intervention group: group one that get 0.5 microgram per kg dexmedetomidine. Intervention 2: Intervention group: group two that get 1 microgram per kg dexmedetomidine.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient consent to enter the study physical condition class I-II according to the standards of the Association of Anesthesiologists body mass index (BMI) less than 40 kg/m2 no pregnancy or breastfeeding no history of coagulopathy or the use of anticoagulants Ejection fraction higher than 30%, no history of conductive heart block (except for first degree heart block and controlled atrial fibrillation) the patient's level of consciousness should be above 14 no acute or chronic hepatitis no history of psychiatric disease no need for complementary Renal treatment or history of kidney failure and no neuropathy no history of drug or alcohol abuse

Exclusion criteria

Exclusion criteria: Allergy to the studied drugs unwillingness of patients to cooperate

Design outcomes

Primary

Measure	Time frame
Study groups, pain score, heart rate, systolic blood pressure, diastolic blood pressure, amount of narcotic drug use, oxygen saturation, duration of walking, duration of stay in ICU. Timepoint: nominal, distance, relative, ratio (in mm Hg), ratio (in mm Hg), ratio (in mg/k), ratio (in percentage), ratio (in minutes), ratio (in minutes). Method of measurement: According to the dose of dexmedetomidine, they are divided into two groups, 0.5 and 1. Based on the criteria, VNS describes the pain between numbers and 10, the number of heartbeats in one minute, systolic blood pressure measured by a sphygmomanometer, diastolic blood pressure measured by a sphygmomanometer, the amount of drug use. Narcotics to control the patient's pain, oxygen saturation percentage using pulse oximeter, time (using clock measurement), time (using clock measurement).	—

Measure

Time frame

Study groups, pain score, heart rate, systolic blood pressure, diastolic blood pressure, amount of narcotic drug use, oxygen saturation, duration of walking, duration of stay in ICU. Timepoint: nominal, distance, relative, ratio (in mm Hg), ratio (in mm Hg), ratio (in mg/k), ratio (in percentage), ratio (in minutes), ratio (in minutes). Method of measurement: According to the dose of dexmedetomidine, they are divided into two groups, 0.5 and 1. Based on the criteria, VNS describes the pain between numbers and 10, the number of heartbeats in one minute, systolic blood pressure measured by a sphygmomanometer, diastolic blood pressure measured by a sphygmomanometer, the amount of drug use. Narcotics to control the patient's pain, oxygen saturation percentage using pulse oximeter, time (using clock measurement), time (using clock measurement).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran Mahmoodi

Ahvaz University of Medical Sciences

mahmoudi-k@ajums.ac.ir+98 61 3311 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026