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The Effectiveness of Mindfulness Integrated Cognitive behavioral Therapy (MiCBT) on the Negative Emotions, improvement of executive function, Emotion Regulation and change of quantitative electroencephalography waves (QEEG) of patients with Multiple Sclerosis

The Effectiveness of Mindfulness Integrated Cognitive behavioral Therapy (MiCBT) on the Negative Emotions, improvement of executive function, Emotion Regulation and change of quantitative electroencephalography waves (QEEG) of patients with Multiple Sclerosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230212057396N1
Enrollment
52
Registered
2023-11-25
Start date
2023-12-31
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Multiple sclerosis. Condition 2: Negative Emotional States. Condition 3: Executive Functions. Condition 4: Quantitative Electroencephalographic Waves. Condition 5: Emotion Regulation. Multiple sclerosis Symptoms and signs involving emotional state Abnormal results of function studies of central nervous system

Interventions

Intervention 1: Intervention group: For the participants of this group, 8 sessions of Mindfulness Integrated Cognitive behavioral Therapy MiCBT, will be implemented within the framework of the Brauno

Sponsors

Neurology Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: The criteria for entering the study are all MS patients with an official diagnosis of MS There are men and women with an age range of 20-50 years. They have at least a diploma. The right is superior. They take beta interferon medicine. All patients completed an informed consent form.

Exclusion criteria

Exclusion criteria: Conditions for not entering the study:MS patients suffer from other psychiatric and neurological disorders. MS patients consumed alcohol or drugs at least two weeks before the study. MS patients received psychological treatment near the study MS patients have epilepsy. They have a history of seizures, brain trauma and other structural brain diseases.

Design outcomes

Primary

MeasureTime frame
Negative Emotional States. Timepoint: Emotional states will be measured once before the implementation of the intervention in the first session (pre-test) and once in the last session after the intervention. Method of measurement: In order to examine emotional states, the original version of DASS has 42 questions, but later it was shortened and reduced to 21 questions. This questionnaire has 21 items including 8 items related to depression (D), 7 items related to anxiety (A) and 6 items related to stress (S).;Executive Functions. Timepoint: Executive functions will be measured once before the implementation of the intervention in the first session (pre-test) and once in the last session after the intervention. Method of measurement: EFQ standard questionnaire of executive functions is used to check executive functions. This questionnaire was compiled by Tos Nejati (2012) and has 30 items and seven subscales. The scoring method is a 5-point Likert scale from almost never (5) to always (1). Its seven subscales include memory (1 to 6), selective attention, questions 7 to 12), decision making (questions 13 to 17), planning (questions 18 to 20), persistent memory (questions 21 to 23), social cognition. (questions 24 to 26) and cognitive flexibility (questions 27 to 30).;Quantitative electroencephalographic waves(QEEG). Timepoint: QEEG will be measured once before the implementation of the intervention in the first session (pre-test) and once in the last session after the intervention. Method of measurement: An EEG device made in Iran under a Canadian license will be used to record the electroencephalogram. In this method, signals and brain waves are recorded by the electrodes on the scalp. This information is entered into the computer and converted into numbers and graphs through QEEG (quantitative brain mapping).;Emotion Regulation. Timepoint: Cognitive emotional regulation will be measured once before the implementation of the intervention in the first session (pre-tes

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Fakhrmand

The University of Alzahra Tehran

A.Fakhrmand@Alzahra.ac.ir+98 21 8805 8925

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026