Diabetic nephropathy. Chapter IV Endocrine, nutritional and metabolic diseases(E00-E90)
Conditions
Interventions
Intervention 1: The intervention group will include 30 patients with diabetic nephropathy with ACR greater than 30. 10 mg melatonin supplement made by Norm Life company will be received twice a day fo
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All patients with type 2 diabetes whose nephropathy was diagnosed through ACR test (>30 mg/gr) during a three-month period
Exclusion criteria
Exclusion criteria: Patients with heart failure Pregnant mothers Lactating mothers Sensitivity to melatonin and its analogues and simultaneous use of interfering drugs such as fluvoxamine,... Patients with urinary tract infections and uncontrolled blood pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the nephroprotective effect of melatonin in patients with diabetic nephropathy. Timepoint: At the beginning of the study, before the intervention and at the end of the work after 3 months, ACR, serum creatinine and sugar of the patients are evaluated by a certain laboratory of the effect of oral melatonin drug. Method of measurement: The effect of melatonin drug on diabetic nephropathy patients is evaluated by using standard laboratory values and laboratory results. | — |
Secondary
| Measure | Time frame |
|---|---|
| Creatine-fasting blood sugar-glomerular filtration. Timepoint: 3 month. Method of measurement: laboratory test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahime Naderi
Mazandaran University of Medical Sciences
Outcome results
None listed