Evaluation of the effect of Iranian Propolis mouthwash on some complications of mandibular impacted third molar surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230212057392N1

Enrollment

Registered

2024-11-03

Start date

2022-06-21

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A patient who needs surgery for an impacted third molar of the mandible (with vertical impaction and grades I and A according to the Pell and Gregory criteria.

Interventions

Intervention 1: Intervention group: After the surgical procedure, the intervention group was given Iranian propolis mouthwash. The mouthwash used contained 1% propolis with a salt concentration of 0.2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Healthy people (ASA I or II) The impacted third molar of the mandible (with vertical impact and grades I and A according to the Pell and Gregory criteria People have not taken any type of antibiotics at least two weeks before surgery

Exclusion criteria

Exclusion criteria: Pregnant and lactating people People under 18 years old People who are allergic to honey Tobacco user

Design outcomes

Primary

Measure	Time frame
Swelling. Timepoint: Before surgery, the second and seventh days after surgery. Method of measurement: The amount of swelling was measured based on the change of facial reference points. The distances between the reference points were measured and recorded using a cloth meter. These distances included the tragus to the midline of the tooth and the angle of the mandible to the midline of the tooth, which was measured with a tape measure.;The maximum amount of mouth opening. Timepoint: Before surgery, the second and seventh days after surgery. Method of measurement: The patient was asked to open his mouth straight as far as he could so that he did not have any jaw deviation and did not suffer pain, then the distance between the upper and lower centers was measured with a ruler.;Pain. Timepoint: Second and seventh day after surgery. Method of measurement: Visual analog scale control and evaluation method.;Number of painkillers used. Timepoint: Second and seventh day after surgery. Method of measurement: questionnaire.	—

Measure

Time frame

Swelling. Timepoint: Before surgery, the second and seventh days after surgery. Method of measurement: The amount of swelling was measured based on the change of facial reference points. The distances between the reference points were measured and recorded using a cloth meter. These distances included the tragus to the midline of the tooth and the angle of the mandible to the midline of the tooth, which was measured with a tape measure.;The maximum amount of mouth opening. Timepoint: Before surgery, the second and seventh days after surgery. Method of measurement: The patient was asked to open his mouth straight as far as he could so that he did not have any jaw deviation and did not suffer pain, then the distance between the upper and lower centers was measured with a ruler.;Pain. Timepoint: Second and seventh day after surgery. Method of measurement: Visual analog scale control and evaluation method.;Number of painkillers used. Timepoint: Second and seventh day after surgery. Method of measurement: questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli nabavizade

Rafsanjan University of Medical Sciences

alinabavizadeh@gmail.com+98 34 3428 0031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026