Condition 1: Multiple Sclerosis (Remitting Relapsing). Condition 2: Stroke. Multiple sclerosis Cerebellar stroke syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Remitting and relapsing Multiple sclerosis disease Having a stroke EDSS score less than 4 in the group of MS patients Follow instructions Spasticity of plantarflexors is equal to or greater than 1 using (MMAS scale) No diabetes Absence of any history of treatment with nerve blockers, or treatment with botulinum toxin A 6 months before entering the study. No history of attacks in MS patients in the last 8 weeks Absence of limitation of passive range of motion of more than 10 percent in ankle dorsiflexion compared to the less involved leg (absence of contracture). Absence of other neurological disorder
Exclusion criteria
Exclusion criteria: Fear of dry needling Recurrent stroke during the patient evaluation and intervention program Occurrence of a new attack in a patient with MS Contraindications to the use of TMS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuromodulation. Timepoint: Before the intervention, After 3 sessions of intervention, and 2 weeks after for follow up. Method of measurement: With Trans-cranial magnetic stimulation parameters, Including motor evoked potential (MEP) amplitude at rest and muscle motor threshold at rest (RMT) and motor evoked potential amplitude ratio in intracortical inhibition protocol (SICI) and motor evoked potential amplitude ratio in intracortical facilitation protocol (ICF).;Spasticity. Timepoint: Before the intervention, after 3 sessions of intervention sessions, and two weeks after the last intervention session for follow-up. Method of measurement: Modified Modified Ashworth Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Balance. Timepoint: Before the intervention, after 3 sessions of intervention sessions, and two weeks after the last intervention session for follow-up. Method of measurement: Timed up and go test and Four Square Step test.;Active and Passive ankle dorsiflexion ROM. Timepoint: Before the intervention, after 3 sessions of intervention sessions, and two weeks after the last intervention session for follow-up. Method of measurement: The evaluation will be done using a goniometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences