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Investigating the effect of zinc gluconate on sperm motility

Investigating changes in sperm motility and expression levels of Dazl, Pmca4 and Bcl2 genes in asthenospermic individuals under the influence of zinc gluconate (ZG) supplementation

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230205057334N1
Enrollment
40
Registered
2023-09-10
Start date
2019-08-26
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthenospermia. Unspecified abnormal finding in specimens from male genital organs

Interventions

Intervention 1: Intervention group: 30 people with asthenospermia who received zinc gluconate supplement (from Simorgh Daru Company) at a dose of 30 mg daily for 90 days. Intervention 2: Control group

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Infertile men, despite having at least one year of unprotected intercourse, natural fertility did not occur in their wives. All men were married and in the age range of 20 to 50 years. According to the expert's opinion and based on the WHO criteria, disorders related to asthenotaratospermia should have been observed in the sperm parameters of at least two samples of their sperm analysis with an interval of 2 weeks.

Exclusion criteria

Exclusion criteria: single men People who had varicocele or other special disease and were diagnosed by a urologist and mentioned in their medical records. Men who had taken special medicine or drugs in the last three months. Infertile men who were not diagnosed by a neurogonadal specialist Participating in another study at the same time

Design outcomes

Primary

MeasureTime frame
Sperm motility. Timepoint: In this study, the effect of zinc gluconate supplementation on sperm motility after 90 days of starting to take this supplement was performed on asthenospermic subjects. Method of measurement: spermogram reports of the patients .

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKiandokht Koohestanian

Islamic Azad University

kian.dokht222@gmail.com+98 935 972 7655

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026