Bronchoscopy for all reasons. Other diseases of bronchus, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: Infusion of 10 mg/kg tranexamic acid in 50mL normal saline will administered 20 minutes before the procedure begins. Intervention 2: Control group: Placebo (normal
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Candidate for elective or emergency flexible bronchoscopy and biopsy (TBLB) Mental health and providing informed consent
Exclusion criteria
Exclusion criteria: Anticoagulant agent consumption Having a known blood Abnormality or coagulopathy Chronic liver disease Chronic kidney disease with a serum creatinine level of more than 2 mg/dL History of seizures Sensitive to antifibrinolytics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemorrhage during the procedure. Timepoint: Intraoperative. Method of measurement: Suction volume. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of local epinephrine or cold saline needed to control bleeding. Timepoint: Intraoperative. Method of measurement: Volume of used fluid.;Duration of operation. Timepoint: intraoperative. Method of measurement: Minune. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Shakeri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed