Urethral reconstruction surgery. Urethral stricture
Conditions
Interventions
Intervention 1: Intervention group (M): One hour before patients enter the operating room, in group M, a dose of clonidine with a dose of 3 microgram/kg and a dose of gabapentin with a dose of 4 mg/kg
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient candidate for urethral reconstruction treatment Mental health and providing informed consent Ability to adhere to patient visit schedule and other relevant protocols American Society of Anesthesiologist (ASA) score I or II Normal kidney and liver function
Exclusion criteria
Exclusion criteria: Any condition that prevents obtaining informed consent. Any other disease, including malignancy, abnormal laboratory tests, psychiatric disease, which in the opinion of the researcher prevents the patient from adhering to the study. Concomitant or uncontrolled illness that, in the researcher's opinion, causes harm to the patient or non-adherence to the study. History of drug addiction, psychoactive drugs and other illegal drug substances
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative opioid consumption (intraop + postop). Timepoint: intraoperative and postoperative. Method of measurement: Based on the amount of narcotics used and recorded in the patient's file. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative opioid consumption. Timepoint: Intraoperative. Method of measurement: Patient file information.;Postoperative opioid consumption. Timepoint: Postoperative up to 24h. Method of measurement: Patient file information.;Postoperative pain. Timepoint: Postoperative up to 24h. Method of measurement: VAS score.;Hospitalization days after surgery. Timepoint: Postoperative. Method of measurement: Hospitalization days.;Postoperative complications (nausea, vomiting, constipation). Timepoint: Postoperative. Method of measurement: Observation/questionnaire.;Intraoperative hemodynamic (HR, MAP). Timepoint: Intraoperative. Method of measurement: Hemodynamic monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Shakeri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed