Skip to content

Nitroglycerin 6% Aloe Vera Gel for Angina

Formulation and Evaluation of Nitroglycerin 6% Aloe Vera Gel for Angina

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230202057310N9
Enrollment
150
Registered
2024-11-21
Start date
2024-12-01
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina pain. Angina pectoris

Interventions

Intervention 1: Intervention group: Group 1 will be given 6% nitroglycerin aloe vera gel. We will apply a measured dose of the nitroglycerin 6% aloe vera gel to the skin (e.g., chest or upper arms) on

Sponsors

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient at least 25-60-year-old of both genders Patient with suspected angina pectoris who undergo coronary angiography Intestinal angina Hypertensive patient Chest pain Pregnant female Breast feeding mothers Symptoms of chest pain

Exclusion criteria

Exclusion criteria: Severe myocardial infarction Cardiogenic shock Severe heart failure Severe hypotension Hypersensitive to medicine Cardiac temponade

Design outcomes

Primary

MeasureTime frame
Reduction in ischemic changes on ECG. Timepoint: Before and after treatment. Method of measurement: ECG: ST-Segment Changes.;Reduction in pain. Timepoint: Before and after treatment. Method of measurement: Numerical pain rating scale (NPRS).;Reduction in the frequency and severity of angina episodes. Timepoint: Before and after treatment. Method of measurement: Angina-specific questionnaires (e.g., the Seattle Angina Questionnaire ).

Secondary

MeasureTime frame
Changes in breathing pattern. Timepoint: before and after treatment. Method of measurement: Breathing pattern.

Countries

Pakistan

Contacts

Public ContactKashaf Khan Anjum Bhutta

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.

kashafbhutta1@gmail.com+92 333 6120602

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026