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Curcumin Gel Along With Ultrasound and Eccentric Exercises On Patellar Tendinopathy Management

Formulation And Evaluation of Curcumin Gel Along With Ultrasound and Eccentric Exercises On Patellar Tendinopathy Management

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230202057310N16
Enrollment
90
Registered
2025-01-22
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellar Tendinopathy. Patellar tendinitis, unspecified knee

Interventions

Intervention 1: Intervention group: Group A: Curcumin-aloe vera gel + ultrasound + eccentric exercises
Ultrasound Application: - Administer therapeutic ultrasound using a frequency of 3 MHz in pulsed mode (intensity of 1–1.5 W/cm²) for 5–10 minutes on the patellar tendon area. Apply curcumin-aloe v

Sponsors

Muhammad Institute of Medical and Allied Sciences, Multan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Participants between 18 to 60 years of age Clinical diagnosis of patellar tendinopathy, confirmed by a qualified healthcare professional Individuals Experiencing chronic patellar tendinopathy symptoms for at least 3 months Moderate severity of symptoms No active inflammatory conditions (e.g., rheumatoid arthritis) or uncontrolled systemic diseases that might affect tendon healing or the safety of treatments.

Exclusion criteria

Exclusion criteria: Individuals with acute (less than 3 months) patellar tendinopathy or other acute knee injuries. Participants with other significant knee conditions (e.g., patellofemoral pain syndrome, osteoarthritis, ligament injuries, or meniscal tears) that may confound the outcomes or interact with the treatments being tested Those who have undergone surgical interventions involving the patellar tendon or knee in the past 6 months. Individuals with uncontrolled systemic diseases, including rheumatoid arthritis, diabetes mellitus, or severe cardiovascular or neurological conditions that could affect tendon healing or physical activity.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Numerical Pain rating scale and Western Ontario and McMaster Universities Osteoarthritis Index.;Knee range of motion (ROM). Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Goniometer.;Tendon thickness. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: ultrasound.;Tendon function. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Victorian Institute of Sport Assessment-Achilles (VISA-A).

Secondary

MeasureTime frame
Muscle Strength. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Hand dynamometer.;Erythrocyte sedimentation rate (ESR). Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Lab test.;Quality of life. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: SF-36 scale.;C-Reactive proteins. Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Lab test.

Countries

Pakistan

Contacts

Public ContactMaliha Khalid Khan

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.

malihatareen1997@gmail.com+92 312 6827130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026