Obesity. Overweight and obesity
Conditions
Interventions
Intervention 1: Intervention group: Group 1: Participants in the drug intervention group will receive e.g., Rosuvastatin 5mg administered orally once daily. This medication has been selected based on
Sponsors
Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Adults aged 18-65 years • Diagnosed with dyslipidemia, defined as elevated levels of total cholesterol (=200 mg/dL) Able and willing to adhere to either drug therapy or a structured exercise program LDL cholesterol (=130 mg/dL) Triglycerides (=150 mg/dL) ow HDL cholesterol (<40 mg/dL for men, <50 mg/dL for women)
Exclusion criteria
Exclusion criteria: History of cardiovascular diseases (e.g., myocardial infarction, angina) Uncontrolled hypertension (=160/100 mmHg) Conditions contraindicating exercise (e.g., musculoskeletal disorders) Recent history of smoking or current tobacco use Current use of lipid-lowering drugs or recent participation in a structured exercise program Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid profile parameters (total cholesterol, LDL, HDL, and triglycerides). Timepoint: 10 weeks. Method of measurement: Blood sample.;Body mass index. Timepoint: 10 weeks. Method of measurement: Calculated from weight and height (measured using a digital scale and stadiometer). | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: 10 weeks. Method of measurement: Measured using a calibrated sphygmomanometer after a 5-minute rest in a seated position.;Waist-to-Hip Ratio, Hip to knee ration and Hip circumference. Timepoint: 10 weeks. Method of measurement: Assessed using a flexible measuring tape.;Quality of life. Timepoint: 10 weeks. Method of measurement: SF-36. | — |
Countries
Pakistan
Contacts
Public ContactMaliha Khalid Khan
Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
Outcome results
None listed