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Curcumin and naproxen gels with ultrasound-enhanced delivery for cervical myofascial pain treatment

Comparative effects of curcumin and naproxen gels with ultrasound-enhanced delivery for cervical myofascial pain treatment

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230202057310N13
Enrollment
105
Registered
2024-12-22
Start date
2025-01-04
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical myofascial pain syndrome. Myositis

Interventions

Intervention 1: Intervention group: Group A: The respective gel (curcumin ) will be applied topically over the affected area at a dose of 2 grams., A therapeutic ultrasound device operating at 1 MHz

Sponsors

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Individuals of all ages diagnosed with cervical myofascial pain syndrome Moderate to severe pain No contraindications to curcumin or naproxen.

Exclusion criteria

Exclusion criteria: Pregnancy , Lactation Severe cervical spine pathology, History of drug allergy, and prior treatment with corticosteroids or other anti-inflammatory medications within four weeks.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 4 weeks. Method of measurement: NPRS.;Cervical ROM. Timepoint: 4 WEEKS. Method of measurement: Goniometry.;Muscle tenderness. Timepoint: 4 weeks. Method of measurement: Pressure pain threshold scale.

Secondary

MeasureTime frame
Serological findings. Timepoint: 4 weeks. Method of measurement: ESR, CRP,IL-6.;Quality of life. Timepoint: 4 weeks. Method of measurement: SF-36 scale.;Functional Status. Timepoint: 4 weeks. Method of measurement: McGill Questionnaire.

Countries

Pakistan

Contacts

Public ContactMaliha Khalid Khan

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.

malihatareen1997@gmail.com+92 312 6827130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026