Skip to content

Fish Oil Supplementation vs Knee Strengthening Exercises: Knee Osteoarthritis Management

Fish Oil Supplementation vs Knee Strengthening Exercises: A Comparative Study in Knee Osteoarthritis Management

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230202057310N10
Enrollment
95
Registered
2024-12-21
Start date
2024-01-07
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteroarthritis. Primary osteoarthritis of other joints

Interventions

Intervention 1: Group A: Fish Oil Supplementation, Dosage: 1,000 mg fish oil capsule taken twice daily for 12 weeks. Intervention 2: Group B: Strengthening Exercises, Supervised physiotherapy sessions

Sponsors

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Clinically diagnosed knee OA (Grade II–III, based on the Kellgren-Lawrence scale). - - Moderate pain severity Able to perform exercises and follow instructions

Exclusion criteria

Exclusion criteria: Severe OA requiring surgery Allergies to fish oil or vegetarian individuals unwilling to consume fish products. Current use of omega-3 supplements or structured physical therapy for OA Significant comorbid conditions (e.g., rheumatoid arthritis, uncontrolled diabetes, cardiovascular diseases).

Design outcomes

Primary

MeasureTime frame
Osteophytes. Timepoint: 12 weeks. Method of measurement: Knee Xray.;Pain, stiffness and ADLs. Timepoint: 12 weeks. Method of measurement: NPRS and WOMAC Scale.;Knee ROM. Timepoint: 12 Weeks. Method of measurement: Goniometry.

Secondary

MeasureTime frame
Knee injury outcome. Timepoint: 12 weeks. Method of measurement: Knee injury outcome score (KOOS).;Quality of life. Timepoint: 12 weeks. Method of measurement: SF-36.

Countries

Pakistan

Contacts

Public ContactMaliha Khalid Khan

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.

malihatareen1997@gmail.com+92 312 6827130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026