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Investigating the effect of furazolidone drug for the treatment of stomach bacterial infection

Comparison of efficacy and safety of quadruple regimens containing furazolidone in patients with Helicobacter pylori infection

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230202057305N1
Enrollment
135
Registered
2023-03-03
Start date
2023-04-03
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H. pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group: First intervention group: furazolidone, proton pump inhibitor, bismuth, amoxicillin. . which is in the form of furazolidone 100 every 12 hours, pentazol 40 every 12

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to No maximum

Inclusion criteria

Inclusion criteria: Confirmation of H. pylori infection in patients by standard diagnostic methods Over seventeen years of age

Exclusion criteria

Exclusion criteria: History of known drug sensitivity to the studied drug regimen pregnancy Having chronic diseases (pulmonary, kidney, liver) Unwillingness to participate in the study Patients treated with other treatment methods such as probiotics, other antibiotics, etc.

Design outcomes

Primary

MeasureTime frame
Eradication and safety of drug regimens containing furazolidone in patients with H. pylori infection. Timepoint: Investigating the eradication rate of H. pylori two weeks after the end of the treatment regimen. Method of measurement: Standard diagnostic methods include RUT, histology staining, bacterial culture, antigen test.

Secondary

MeasureTime frame
H. pylori eradication, drug safety. Timepoint: Two weeks after the end of the eradication treatment. Method of measurement: Urea breath test, fecal antigen, bacterial culture, histology.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Maryam Moghadam Ziabari

Shahid Beheshti University of Medical Sciences

maryam.moghadam201@gmail.com+98 13 4468 2868

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026