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Conditions
Interventions
Intervention 1: Intervention group: 500 mg bromelain drug (Permon Amin Pharmaceutical Company) along with acetaminophen 325 mg every 8 hours (three times a day) and corticosteroids including dexametha
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 35 Years
Inclusion criteria
Inclusion criteria: Needing mandibular third molar surgery Age between 17-35 years Semi-embedded mesiangular mandibular third molar teeth
Exclusion criteria
Exclusion criteria: Patients who have taken painkillers or other drugs within 24 hours before surgery. have a history of addiction to drugs or painkillers Patients who are pregnant or breastfeeding, or have a known sensitivity to analgesics, common non-steroidal anti-inflammatories or cyclooxygenase-2 inhibitors. Those who have a history of nasal polyps, bronchospasm or angioedema caused by non-steroidal anti-inflammatories. Patients who were not able to take medicine orally
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 1, 3 and 7 days after surgery. Method of measurement: A visual analogue scale (VAS), with 10 points, will be evaluated from 0 for "no pain" to 10 for "worst possible pain".;Trismus. Timepoint: 1, 3 and 7 days after surgery. Method of measurement: The degree of trismus is also measured by measuring the inter-incisal distance using a measuring caliper and the results are reported with an accuracy of 0.01 mm. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactIlnaz Ghanbari
Shiraz University of Medical Sciences
Outcome results
None listed