Effects of carbon dioxide insufflation rate in laparoscopic sigmoidectomy surgery.

Investigating the effect of carbon dioxide gas insufflation rate on shoulder pain after surgery in laparoscopic sleeve gastrectomy candidates: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230129057271N4

Enrollment

Registered

2025-10-13

Start date

2025-10-23

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Interventions

Intervention 1: Intervention group: Injecting carbon dioxide gas during laparoscopy (after the patient is fully anesthetized and at the beginning of laparoscopy) at a rate of 2.5 liters per minute int

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 60 years old Physiological status ASA I-II Body mass index between 30 and 45 Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Bleeding during surgery Previous upper gastrointestinal surgery Long-term use of NSAIDs or other painkillers for chronic pain Patients with previous heart surgery Left ventricular ejection fraction less than 40% Myocardial infarction recorded in the past six weeks Congestive heart failure Patients with high blood pressure History of drug addiction Need for painkillers in addition to the injected painkillers Need for drain placement after surgery

Design outcomes

Primary

Measure	Time frame
Shoulder pain after surgery. Timepoint: 2,6,12,24,48 hours after surgery. Method of measurement: Using the VAS scale.;The patient's heart rate per minute. Timepoint: Once after anesthesia and just before carbon dioxide injection, ten minutes after carbon dioxide gas injection, 20 minutes, 30 minutes, and 60 minutes after gas injection, at the end of surgery, 5 minutes, and 10 minutes after arriving in the recovery room. Method of measurement: Using a monitoring device.;Mean arterial blood pressure. Timepoint: Once after anesthesia and just before carbon dioxide injection, ten minutes after carbon dioxide gas injection, 20 minutes, 30 minutes, and 60 minutes after gas injection, at the end of surgery, 5 minutes, and 10 minutes after arriving in the recovery room. Method of measurement: After measuring systolic and diastolic blood pressure using a monitoring device, the mean arterial pressure will be obtained using the following formula: MAP = (SBP + 2DBP)/3.	—

Measure

Time frame

Shoulder pain after surgery. Timepoint: 2,6,12,24,48 hours after surgery. Method of measurement: Using the VAS scale.;The patient's heart rate per minute. Timepoint: Once after anesthesia and just before carbon dioxide injection, ten minutes after carbon dioxide gas injection, 20 minutes, 30 minutes, and 60 minutes after gas injection, at the end of surgery, 5 minutes, and 10 minutes after arriving in the recovery room. Method of measurement: Using a monitoring device.;Mean arterial blood pressure. Timepoint: Once after anesthesia and just before carbon dioxide injection, ten minutes after carbon dioxide gas injection, 20 minutes, 30 minutes, and 60 minutes after gas injection, at the end of surgery, 5 minutes, and 10 minutes after arriving in the recovery room. Method of measurement: After measuring systolic and diastolic blood pressure using a monitoring device, the mean arterial pressure will be obtained using the following formula: MAP = (SBP + 2DBP)/3.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Imani

Hamedan University of Medical Sciences

sinaghasemi19980@gmail.com+98 901 669 0780

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026