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Intraperitoneal lavage with normal saline solution containing bupivacaine, normal saline containing magnesium sulfate, and normal saline alone, in patients who are candidates for laparoscopic sleeve gastrectomy

Comparison of the efficacy of intraperitoneal lavage with normal saline solution containing bupivacaine, normal saline containing magnesium sulfate and normal saline alone, on postoperative complications in patients who are candidates for laparoscopic sleeve gastrectomy surgery: a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230129057271N2
Enrollment
105
Registered
2025-05-15
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Interventions

Intervention 1: Intervention group: Intraperitoneal lavage with 30 ml of 0.25% bupivacaine without normal saline. Intervention 2: Intervention group: Intraperitoneal lavage with 30 ml of 10% magnesium

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA physiological status I-II Body mass index between 30 and 45 Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with known allergies to bupivacaine or magnesium sulfate Long-term use of NSAIDs or other painkillers for chronic pain Patients with established hepatic or renal disorders Patients with previous heart surgery Left ventricular ejection fraction less than 40% myocardial infarction recorded in the past six weeks Congestive heart failure Patients with chronic abdominal or pelvic pain syndrome Patient with known hypermagnesemia

Design outcomes

Primary

MeasureTime frame
Postoperative surgical site pain. Timepoint: 1, 2, 4, 6, 12 and 24 hours after surgery. Method of measurement: Using the VAS scale.;Shoulder pain after surgery. Timepoint: 2,6,12,24,48 hours after surgery. Method of measurement: Using the VAS scale.;Number of times the patient requested painkillers. Timepoint: The first 24 hours after surgery. Method of measurement: Counting the number of requests.;Nausea and vomiting after surgery. Timepoint: The first 24 hours after surgery. Method of measurement: have or does not have.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Imani

Hamedan University of Medical Sciences

sinaghasemi19980@gmail.com+98 901 669 0780

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026