laryngeal cancer. Malignant neoplasm of larynx
Conditions
Interventions
Intervention group: Patients with early stage laryngeal cancer are treated with hypofractionated radiotherapy with a total dose of 54 Gy in 18 sessions..
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Definitive diagnosis of squamous cell carcinoma of the larynx based on pathology report Glottic lesions T1-2 No involvement of neck lymph nodes (N0) 18 to 75 years old Performance level based on ECOG less than 3
Exclusion criteria
Exclusion criteria: Other malignant histologies of the larynx except squamous cell carcinoma History of head and neck radiotherapy Previous history of chemotherapy Previous history of malignancy except skin BCC History of diabetes or uncontrolled blood pressure History of tracheostomy With a history of laser microsurgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathologic complete response. Timepoint: Post operation. Method of measurement: Pathologic examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Weekly during intervention course. Method of measurement: Radition therapy toxicity critria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Elahi
Shiraz University of Medical Sciences
Outcome results
None listed