The dental anesthetic effect of articaine compared to lidocaine

Evaluation of anesthetic efficacy of incisive nerve block with articaine 4% and epinephrine 1/200000 compared to inferior alveolar nerve block with lidocaine 2% and epinephrine 1/80000 during mandibular second premolar extraction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230128057259N1

Enrollment

Registered

2023-02-14

Start date

2023-02-02

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental problems. Encounter for screening for other specified diseases and disorders

Interventions

Intervention 1: Intervention group: Teeth will be numbed with incisive block anesthesia technique with articaine 4% along with epinephrine 1/200000 (dentacaine by Elixir company). Intervention 2: Inte

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consent to participate in the study Absence of systemic problem

Exclusion criteria

Exclusion criteria: Allergy to anesthetics Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
Time to reach complete anesthesia. Timepoint: Immediately after the end of all injections. Method of measurement: Immediately after the end of all injections; The duration of lip numbness will be measured with the lip numbness index and by a stopwatch.;The need for additional anesthesia injection. Timepoint: After starting the extraction. Method of measurement: After starting the extraction and in order to maintain complete anesthesia and painlessness of the patient during the tooth extraction, if necessary, an injection of supplementary anesthesia (pdl injection) will be performed. (Extract will not be performed until optimal anesthesia is achieved).;The amount of pain. Timepoint: During tooth extraction. Method of measurement: Visual Analogue Scale.	—

Measure

Time frame

Time to reach complete anesthesia. Timepoint: Immediately after the end of all injections. Method of measurement: Immediately after the end of all injections; The duration of lip numbness will be measured with the lip numbness index and by a stopwatch.;The need for additional anesthesia injection. Timepoint: After starting the extraction. Method of measurement: After starting the extraction and in order to maintain complete anesthesia and painlessness of the patient during the tooth extraction, if necessary, an injection of supplementary anesthesia (pdl injection) will be performed. (Extract will not be performed until optimal anesthesia is achieved).;The amount of pain. Timepoint: During tooth extraction. Method of measurement: Visual Analogue Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Hashemi

Tabriz University of Medical Sciences

mohsen.hashemi3263@gmail.com+98 44 3344 4598

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026