A comparative study of injecting platelet-rich plasma solution versus normal saline injection on olfactory outcomes following endoscopic sinus surgery in patients with chronic sinusitis accompanied by nasal polyps.

A comparative randomized study of injecting platelet-rich plasma solution versus normal saline injection on olfactory outcomes following endoscopic sinus surgery in patients with chronic sinusitis accompanied by nasal polyps : a single-center clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230127057244N3

Enrollment

Registered

2024-12-29

Start date

2025-01-20

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Sinusitis. Chronic pansinusitis

Interventions

Intervention 1: Intervention group: Injection of platelet-rich plasma solution on olfactory outcome after endoscopic sinus surgery in sick patients to chronic sinusitis with polyps. Intervention 2: Co

Eligibility

Sex/Gender

All

Age

15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients aged 15 to 50 years with nasal polyps. Having different severities of olfactory disorder based on the olfactory recognition test score and duration of anosmia less than 2 years.

Exclusion criteria

Exclusion criteria: Head Truma Revision Sinonasal Surgery Smoking Congenital Anosmia Systemic Disorder

Design outcomes

Primary

Measure	Time frame
Olfactory Outcomes. Timepoint: At entrance time to trial and 6 months later. Method of measurement: Sino-nasal Outcome Test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadReza Firozifar

Tehran University of Medical Sciences

mrfirouzifar@sina.tums.ac.ir+98 21 6670 6106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026