efficacy of using the vaginal probiotic suppository on genital warts

Evaluating the efficacy of vaginal probiotic suppository along with cryotherapy and its comparison with cryotherapy alone in the improvement of genital wart lesions

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230124057201N5

Enrollment

Registered

2025-11-09

Start date

2026-01-21

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genital wart. Anogenital (venereal) warts

Interventions

Intervention 1: Intervention group: This group includes combination therapy. Patients receive cryotherapy for four sessions at three weeks interval, while receiving three ten-day courses of probiotic

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Female patients Married Without underlying disease Presence of more than three wart lesions in the genital area (perineum and anus)

Exclusion criteria

Exclusion criteria: single patients Patients with immunodeficiency patients with high grade HPV and malignant lesions

Design outcomes

Primary

Measure	Time frame
Number of genital warts. Timepoint: Four sessions at three-weeks interval. Method of measurement: Counting the number of lesions per session.	—

Secondary

Measure	Time frame
Size of genital wart lesions. Timepoint: Four sessions at three-weeks interval. Method of measurement: measuring with scaled ruler.;Physician global assessment questionnaire. Timepoint: At the end of the study. Method of measurement: Rated Likert scale questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Aryanian

Tehran University of Medical Sciences

z_aryanian@yahoo.com+98 21 5563 0853

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026