Psoriasis. Diseases of the skin and subcutaneous tissue
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive 1 tablet of alphalipoic acid at a dose of 600 mg with water for 8 weeks. Alphalipoic acid tablets are purchased from Karen B. Al
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Diagnosis of psoriasis based on the PASI criteria by a dermatologist PASI number above 20 in psoriasis patients
Exclusion criteria
Exclusion criteria: Any history of alcohol and tobacco use Breastfeeding and pregnancy or pregnancy intention within the next 3 months Use of biological drugs, corticosteroids, methotrexate, antibiotics Having diabetes and the presence of any diagnosed neoplasia or malignancy Use of antioxidants and omega-3 supplements in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ESR. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the intervention. Method of measurement: Elisa.;ALT, AST, ALKP. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the intervention. Method of measurement: Elisa.;TG, TC, HDL, LDL. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the intervention. Method of measurement: Elisa. | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP. Timepoint: The beginning of the intervention (before the intervention) and after 8 weeks of the intervention. Method of measurement: Elisa.;MDA. Timepoint: The beginning of the intervention (before the intervention) and after 8 weeks of the intervention. Method of measurement: Elisa. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsorayia ebrahim pour koujan
Tehran University of Medical Sciences
Outcome results
None listed