Comparison of the effects of lidocaine and bupivacaine in preventing oculocardiac reflex in strabismus surgery

Comparison of the effectiveness of lidocaine and bupivacaine Sub-tenon injection in preventing oculocardiac reflex in strabismus surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230122057174N1

Enrollment

120

Registered

2023-02-01

Start date

2023-03-01

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus. Unspecified strabismus

Interventions

Intervention 1: Intervention group A: After induction of anesthesia, 4cc of bupivacaine (brand name Marcaine) will be injected into the subtenon space of the operated eye. Intervention 2: Intervention

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA grade I or II (American Society of Anesthesiology classification) Patients between 18 and 35 years old Candidate patients for Sub-Tenon's block

Exclusion criteria

Exclusion criteria: Patients with ASA grade III or IV (American Society of Anesthesiology classification) Positive history of heart disease Positive history of hyperthyroidism Positive history of coagulation disorders Pregnant women Patient refusal

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: Every 5 minutes during the operation. Method of measurement: Monitoring.;Mean arterial pressure. Timepoint: Every 5 minutes during the operation. Method of measurement: Monitoring.;Pain. Timepoint: One hour after the operation. Method of measurement: Questionnaire and Numerical Pain Rating Scale (NRS).;Nausea. Timepoint: One hour after the operation. Method of measurement: History taking.;Vomiting. Timepoint: One hour after the operation. Method of measurement: History taking.	—

Measure

Time frame

Heart rate. Timepoint: Every 5 minutes during the operation. Method of measurement: Monitoring.;Mean arterial pressure. Timepoint: Every 5 minutes during the operation. Method of measurement: Monitoring.;Pain. Timepoint: One hour after the operation. Method of measurement: Questionnaire and Numerical Pain Rating Scale (NRS).;Nausea. Timepoint: One hour after the operation. Method of measurement: History taking.;Vomiting. Timepoint: One hour after the operation. Method of measurement: History taking.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Dehghanpoor farashah

Shiraz University of Medical Sciences

arefaneh_2002@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026