Comparing the effect of physiotherapy combined with manual lymphatic derenage massage with physiotherapy alone and manual lymphatic derenage massage alone on pain and volume of upper limb on breast cancer patients with lymphedema

Comparing the effect of physiotherapy combined with manual lymphatic derenage massage with physiotherapy alone and manual lymphatic derenage massage alone on pain and volume of upper limb on breast cancer patients with lymphedema: A randomized controlled trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230121057168N1

Enrollment

Registered

2023-07-01

Start date

2023-06-05

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoedema. Postmastectomy lymphoedema syndrome

Interventions

Intervention 1: Intervention group: Lymphatic drainage manual massage + physiotherapy In the intervention group of physiotherapy + MLD massage, patients are initially subjected to FES electrical stimu

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Female patients with lymphedema of at least 10% compared to healthy limb At least six months have passed since the patient's cancer treatment Having moderate physical activity in daily activities

Exclusion criteria

Exclusion criteria: Active malignancy Recurrence of breast cancer high blood pressure Uncontrolled heart disease Patients with bilateral lymphedema venous insufficiency Low physical activity and inability to perform daily activities

Design outcomes

Primary

Measure	Time frame
The pain of patients is evaluated with the NRS scale. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The pain of patients is evaluated with questionnaire of the NRS scale.;The size of the affected limb and the healthy limb will be measured. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The circumference of the uper limb is measured using a tape measure.	—

Measure

Time frame

The pain of patients is evaluated with the NRS scale. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The pain of patients is evaluated with questionnaire of the NRS scale.;The size of the affected limb and the healthy limb will be measured. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The circumference of the uper limb is measured using a tape measure.

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Secondary

Measure	Time frame
ROM of the upper limb joints is measured. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The range of motion of the shoulder is measured using a goniometer.;The performance of patients is evaluated. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The performance of patients is evaluated using the Upper Limb Functional Index (ULFI) questionnaire.;The degree of disability of the patients is evaluated. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The degree of disability of the patients is evaluated with the Shortened Disabilities of the Arm, Shoulder and Hand Questionnaire (QuickDASH).;Quality of life of patients will be examined. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: Quality of life of patients will be examined using the Lymphedema Life Impact Scale (LLIS) questionnaire.	—

Measure

Time frame

ROM of the upper limb joints is measured. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The range of motion of the shoulder is measured using a goniometer.;The performance of patients is evaluated. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The performance of patients is evaluated using the Upper Limb Functional Index (ULFI) questionnaire.;The degree of disability of the patients is evaluated. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: The degree of disability of the patients is evaluated with the Shortened Disabilities of the Arm, Shoulder and Hand Questionnaire (QuickDASH).;Quality of life of patients will be examined. Timepoint: Befor treatment After 15 sessions after 1 month. Method of measurement: Quality of life of patients will be examined using the Lymphedema Life Impact Scale (LLIS) questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Mostafaee

Mashhad University of Medical Sciences

neda_mostafaee@yahoo.com+98 51 3884 6710

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026