The effect of NBS powder in treatment of patients with multi-drug resistant tuberculosis

Evaluation of NBS herbal powder effects as a complementary medicine on the recovery of patients with multi-drug resistant tuberculosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230116057135N1

Enrollment

Registered

2023-01-21

Start date

2023-02-20

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory tuberculosis. Respiratory tuberculosis

Interventions

Intervention 1: Intervention group: Patients in intervention group in addition to the standard antibiotic treatment regimen + Nutrition Bio-Shield (NBS) powder will be prescribe is below: Dosage of NB

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with multi-drug resistant tuberculosis Patients over 18 years old

Exclusion criteria

Exclusion criteria: The patient's withdrawal from the study Patients with any other chronic disease such as diabetes, cardiovascular disease, etc. Patients who have received supplements of vitamin D, zinc, B vitamins and other micronutrients in the last month. Patients who do not come for follow-up treatment at specified intervals Pregnant and lactating mothers Use of corticosteroids and immunosuppressive drugs Observing any drug sensitivity (especially digestive sensitivity to gluten) as determined by the attending physician Deterioration of the patient's clinical symptoms due to the consumption of Nutrition Bio-Shield (NBS) powder, as determined by the attending physician Patient's death during common and selective treatments (in case of death, the patient's information is fully recorded and laboratory tests are performed along with other samples to determine the possible effect of the drug on the patient's death)

Design outcomes

Primary

Measure	Time frame
Microbial load. Timepoint: Before of the intervention, monthly monitoring, after of the intervention. Method of measurement: Examining the Ziehl–Neelsen staining slide, colony count.;Measurement of white blood cells. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Cell Counter.;Measurement of inflammatory factors. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Gold Standard Methods (Westergren method for ESR, Electrochemical Immunoassay for CRP).	—

Measure

Time frame

Microbial load. Timepoint: Before of the intervention, monthly monitoring, after of the intervention. Method of measurement: Examining the Ziehl–Neelsen staining slide, colony count.;Measurement of white blood cells. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Cell Counter.;Measurement of inflammatory factors. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Gold Standard Methods (Westergren method for ESR, Electrochemical Immunoassay for CRP).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Mosadegh

Tehran University of Medical Sciences

m-mosadegh@razi.tums.ac.ir+98 935 563 3390

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026