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comparison of the effectiveness of 5-FU and tacrolimus ointment in the treatment of vitiligo vulgaris

comparison of the effectiveness of 5-FU and tacrolimus ointment in the treatment of vitiligo vulgaris

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230115057128N1
Enrollment
40
Registered
2023-02-19
Start date
2023-01-21
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo vulgaris. Vitiligo

Interventions

Intervention 1: Intervention group 1: For the first intervention group, the use of 0.1% tacrolimus topical ointment on body lesions will be prescribed twice a day (in the morning after waking up and a

Sponsors

Ilam University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: The presence of at least two vitiligo lesions in the upper, lower and trunk limbs similar in size and color (if the patient had several depigmented lesions, among them two lesions that were similar in size and color were selected would be) Age above 12 years have the possibility to refer and follow up Consent based on participating in the study Not using topical treatments in the last month The steady or progressive course of the disease in a person Occupancy of at least 10% of the body surface by this disease Not having an immune deficiency

Exclusion criteria

Exclusion criteria: Patients with skin lesions on the face Cases of segmental vitiligo pregnancy Inability to track treatment results

Design outcomes

Primary

MeasureTime frame
Size of the lesion. Timepoint: Examining the lesions at the beginning of the study and the second, fourth and sixth months after the start of treatment. Method of measurement: VASI scoring system.;Percentage of pigmentation. Timepoint: Examining the lesions at the beginning of the study and the second, fourth and sixth months after the start of treatment. Method of measurement: VASI scoring system.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Raoufi

Ilam University of Medical Sciences

dr.raoufi.f@gmail.com+98 84 3224 0029

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026