depression. Major depressive disorder, recurrent, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Anti-inflammatory diet. Intervention 2: Control group: Normal diet.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Female gender Being between the ages of 20 and 60 Suffering from clinical depression with moderate or greater severity and diagnosed by a psychiatrist.
Exclusion criteria
Exclusion criteria: Pregnant or lactating Decision to get pregnant in the future Being a smoker or addicted to other tobacco products Having intense physical activity as a professional athlete There has been a change in the type and dose of medication used for mental disorders during the last two months All types of antibiotics have been used during the two have consumed in the last month Have consumed any amount of probiotic supplements during the last two months Have been exposed to the coronavirus All types of cancer, heart, and brain strokes, and multiple, CKD, have been affected in The last month, as well as diseases such as diabetes Sclerosis or other autoimmune diseases in the last three months Taking omega 3 supplements and Suffering from various eating disorders are also part of the criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Moderate depression score based on Hamilton's 17-item questionnaire (score 14 to 17). Timepoint: At the beginning and 8 weeks after the start of the intervention. Method of measurement: Hamilton's 17-item questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut microbiota. Timepoint: At the beginning and 8 weeks after the start of the intervention. Method of measurement: real-time PCR.;Inflammatory biomarkers. Timepoint: At the beginning and 8 weeks after the start of the intervention. Method of measurement: Elisa. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactahmad esmaillzadeh
Tehran University of Medical Sciences
Outcome results
None listed