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Comparison of the effect of 0.2% chlorhexidine solution and toothbrush in the prevention of oral lesions in intubated patients hospitalized in the intensive care unit

Comparison of the effect of 0.2% chlorhexidine solution and toothbrush in the prevention of oral lesions in intubated patients hospitalized in the intensive care unit

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230105057051N1
Enrollment
108
Registered
2023-07-11
Start date
2023-07-22
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral lesions.

Interventions

Intervention 1: Control group: Mouthwash group (group A) is performed with 0.2% chlorhexidine solution according to the routine method of the department. In this way, 10 ml of chlorhexidine is poured

Sponsors

Shaheed Rajaie Cardiovascular Medical & Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age above 18 years Having an oral tracheal tube for at least 3 days No wounds and severe injuries in the mouth Not having hepatitis B disease Not having HIV Not having coagulation problems Insensitivity to chlorhexidine Not having artificial teeth

Exclusion criteria

Exclusion criteria: Transfer of the patient from the intensive care unit during the study period Death of the patient during the study Allergic reaction Limitations in performing the technique Risk of aspiration Unwillingness to continue the study on the part of the legal guardians of the patients Perform tracheostomy during the study Endotracheal tube extubeation during the study period

Design outcomes

Primary

MeasureTime frame
Oral hygiene method. Timepoint: It is done at 7:00 and 19:00 during 3 days (6 times in total). Method of measurement: It is checked using BOAS and MPS tools and recorded in the checklist.

Secondary

MeasureTime frame
Oral health score. Timepoint: Intervention is done before each turn and recorded in the relevant checklist. Method of measurement: It is checked using BOAS and MPS tools and recorded in the checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahnaz Shamseh

Shaheed Rajaie Cardiovascular medical & Research Center

mashamceh@gmail.com+98 66 3343 5542

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026