Skip to content

The effect of lumbar manipulation on neurometabolites of the thalamus in non-specific chronic low back pain patients

The effect of lumbar manipulation on neurometabolites of the thalamus in non-specific chronic low back pain patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230103057029N1
Enrollment
32
Registered
2023-01-30
Start date
2023-01-21
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unspecific Chronic Low Back Pain. Dorsalgia, unspecified

Interventions

Intervention 1: Intervention group: spinal manipulation of lumbar and pelvic.Patients will receive 3 sessions of manipulation therapy (every other day) of the lumbar spine and pelvis. Intervention 2:

Sponsors

Behbahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 16 patients with non-specific chronic back pain for more than three months, in the age range of 20 to 50 years 16 healthy people without any pain in the age range of 20 to 50 years.

Exclusion criteria

Exclusion criteria: Patients with chronic back pain with specific neurological origin and specific pathology (tumor, etc.), patients with neurological and rheumatoid disorders, diabetes, patients with broken ribs, vertebrae, and pelvis, tailbone syndrome, abdominal aortic aneurysm, neoplasm , neuropathy and radiculopathy, osteoporosis, fibromyalgia, pain in other areas of the body, injury and use of drug during the study. People who used antidepressants and anxiety medications Patients with non-specific chronic back pain who were treated for the last three months.

Design outcomes

Primary

MeasureTime frame
Thalamus Neurometabolits. Timepoint: Before and 5 weeks after the intervention. Method of measurement: Recording the neurometabolic map of the thalamus by magnetic resonance spectroscopy(MRS).

Secondary

MeasureTime frame
Pain Intencity. Timepoint: Before and 5 weeks after the intervention. Method of measurement: Numerical Rating Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDaryoush Didehdar

Behbahan University of Medical Sciences

dary1358@gmail.com+98 917 148 7091

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026