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Effect of morphin in prognose of Anterior MI

Evaluation of the effect of morphine administration on serum CKMB level, ST segment depression and TIMI effect in patients with first acute anterior myocardial infarction who underwent primary coronary angioplasty.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230102057018N1
Enrollment
200
Registered
2023-04-24
Start date
2023-03-21
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Anterior ST Elevatiom Myocardial Infarction. ST elevation (STEMI) myocardial infarction of anterior wall

Interventions

Intervention 1: Intervention group: For this group, morphine sulfate is injected in the lab coat and on the angiography bed with a dose of 1 mg intracoronary and 3 mg intravenous. 3 mg of intravenous

Sponsors

Research Assistant of Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Typical cardiac chest pain lasting at least 20 minutes ST segment elevation of at least 1 mm repeated in two consecutive leads Q wave not seen with ST segment elevation patient's first acute anterior myocardial infarction A heart attack has occurred in the last 6 hours initial TIMI score is 0 or 1 no morphine injection in the emergency room or before

Exclusion criteria

Exclusion criteria: receiving fibrinolytic receiving cardiac electric shock resuscitating the patient being intubated having VT or VF arrhythmia history of CABG complete heart block respiratory failure history of liver cirrhosis early TIMI flow 2 or more

Design outcomes

Primary

MeasureTime frame
Coronary timi flow. Timepoint: in angiographic last view. Method of measurement: According to the international definition of coronary Timi Flow.

Secondary

MeasureTime frame
The degree of ST segment depression in the patient's ECG. Timepoint: 90 minutes after the patient enters the CCU. Method of measurement: Obtaining an ECG by the patient's nurse and reading it by a cardiologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParviz Shahaby

Research Assistant of Tabriz University of Medical Sciences

Tohidyahyapoor1382@gmail.com009841333900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026