Effectiveness of transdiagnostic treatment on psychological parameters in multiple sclerosis

Effectiveness of unified protocol of transdiagnostic treatment on psychological symptoms, fatigue, emotion regulation, health anxiety, sleep quality, and sexual satisfaction in patients with multiple sclerosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221230056986N1

Enrollment

Registered

2023-06-17

Start date

2023-08-23

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group: 12 sessions of online psychotherapy based on unified protocol of transdiagnostic treatment. Intervention 2: Control group: Not receiving treatment intervention.

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Confirmation of relapsing-remitting multiple sclerosis diagnosis by neurologist Age least 20 years Being sexually active Mastery in Persian language and reading and writing literacy Fixed dosage of medicine from 3 months before beginning the treatment Being physically able to participate in weekly sessions Not being diagnosed with severe psychiatric disorders Not being diagnosed with another serious or chronic physical illness Not having the history of receiving psychological treatments

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Psychological symptoms. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Depression, Anxiety, Stress Scale (DASS-21).;Fatigue. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Fatigue Severity Scale (FSS).;Quality of sleep. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Pittsburgh Sleep Quality Index (PSQI).;Sexual Satisfaction. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Larson Sexual Satisfaction Questionnaire (LSSQ).;Emotion regulation. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Cognitive Emotion Regulation Questionnaire (SERQ).;Health anxiety. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Health Anxiety Questionnaire (HAQ).	—

Measure

Time frame

Psychological symptoms. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Depression, Anxiety, Stress Scale (DASS-21).;Fatigue. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Fatigue Severity Scale (FSS).;Quality of sleep. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Pittsburgh Sleep Quality Index (PSQI).;Sexual Satisfaction. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Larson Sexual Satisfaction Questionnaire (LSSQ).;Emotion regulation. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Cognitive Emotion Regulation Questionnaire (SERQ).;Health anxiety. Timepoint: Before intervention, after intervention, three month after intervention. Method of measurement: Health Anxiety Questionnaire (HAQ).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mahdi Katani

Shahid Beheshti University of Medical Sciences

amir.katani.1993@gmail.com+98 21 4411 6678

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026