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Comparing the effect of lidocaine injection with articaine injection in reducing pain in the treatment of bilateral molar implants in the lower jaw

Comparing the effect of infiltration lidocaine and articaine injection on pain intensity in bilateral mandibular molar implant treatment, a clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221227056940N2
Enrollment
30
Registered
2025-07-04
Start date
2025-07-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edentulous in the molar area of the mandible.

Interventions

Intervention 1: Intervention group: For the first intervention group, 1.8 ml of 2% lidocaine from Pakhsh Daru Company (made in Iran) was administered once during surgery by injection into the surgical

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients requiring implant treatment due to loss of bilateral mandibular molar teeth; patients with systemic conditions ASA class I and II; patients aged 18 to 65 years; implant site healing and no need for bone reconstruction; at least 3 months after extraction treatment; no lucency or unusual opacity on radiography; informed consent to participate in the project.

Exclusion criteria

Exclusion criteria: Prohibition of the use of epinephrine with a preservative; use of narcotics, sedatives, NSAIDs, psychotropic drugs and anything that changes the patient's perception of pain; poor pulp health of adjacent teeth; performing implant surgery as a fresh socket; presence of neurological orofacial symptoms; presence of infection in the surgical area; pregnant and lactating women; presence of severe heart disease; dissatisfaction to participate in the study or withdrawal from it.

Design outcomes

Primary

MeasureTime frame
Pain intensity score. Timepoint: During soft tissue cutting. Method of measurement: Visual Analog Scale (VAS).;Pain intensity score. Timepoint: In the bone drilling stage. Method of measurement: Visual Analog Scale (VAS).

Secondary

MeasureTime frame
Pain intensity score. Timepoint: 1 and 4 hours after surgery. Method of measurement: Visual Analog Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactErmiya Asghari

Gorgan University of Medical Sciences

asghari.ermiya@gmail.com+98 17 3262 7823

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026