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Investigating the effect of liquid PRF in maintaining dental socket

The Comparison of clinical, radiographic and histological outcomes of socket preservation following tooth extraction using allograft with and without injectable platelet rich fibrin

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221227056937N1
Enrollment
15
Registered
2023-01-12
Start date
2022-11-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maintaining the socket dimensions of the tooth after tooth extraction for implant treatment.

Interventions

Intervention 1: Control group: Allograft group without I-PRF substance.the socket is filled with allograft material (Itp Regen) and covered with collacone. Then, a cross stitch (figure of eight) will

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient must be over 18 years old single root tooth that needs to be pulled and replaced with dental implant restoration. Remaining bone support more than 50%

Exclusion criteria

Exclusion criteria: The presence of any systemic disease or disease that affects bone healing Taking any medicine that is effective on bone healing Existence of severe or uncontrolled systemic disease Pregnancy Daily consumption of 10 cigarettes or more History of radiotherapy Having a contraindication for implant placement Using any prosthesis in the intervention site Need for antibiotic prophylaxis Presence of widespread infection near the intervention site

Design outcomes

Primary

MeasureTime frame
Alveolar socket width: the width of the alveolar bone in the midbuccal region from the buccal side to the lingual side of the drawn tooth. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months after the intended treatment. Method of measurement: The digital caliper calculates the width of the alveolar bone in the midbuccal area from the buccal to the lingual side of the extracted tooth with an accuracy of 0.01 mm.

Secondary

MeasureTime frame
Radiographic evaluation. Timepoint: The beginning of the study (before the intervention) and 3 months after the intervention. Method of measurement: By using CBCT deviceThe alveolar socket is evaluated in the buccolingual and mesiodistal dimensions at 1, 3 and 5 mm sections.;Amount of vital bone. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months after the intervention. Method of measurement: Presence of osteocyte and osteoblast along with bone trabeculae in bone tissue through light microscope evaluation.;Socket vertical height in the midbuccal region. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months after the intervention. Method of measurement: The height of the alveolar bone in the midbuccal area from the CEJ of the adjacent tooth to the edge of the alvelar crest was measured with a digital calliper to the accuracy of 0.01 mm.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmasoud Hatami

Shahid Beheshti University of Medical Sciences

Hatamimassod@yahoo.com+98 21 6694 0647

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026