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Stem cell in Kienbock's disease

Evaluation of the Kienbock's disease treatment using Peripheral blood stem cell transplantation (PBSCT)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221223056902N1
Enrollment
20
Registered
2023-07-08
Start date
2023-10-23
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kienböck disease of adults. Kienbock's disease of adults

Interventions

Intervention 1: Intervention group: radial shortening osteotomy, as the standard treatment for Keinboch's disease, plus platelet gel transplantation containing peripheral blood stem cells and deminera

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Radiologic Diagnosis of the Kienbock's disease by a hand surgeons No previous history of Kienbock's disease-related surgery

Exclusion criteria

Exclusion criteria: Incidence of any comorbid disorders that might increase the risk of surgery including cardiovascular disorders, uncontrolled diabetes, rheumatic diseases such as rheumatoid arthritis, cancers, hepatic and renal failure and etc. Patients with hematological or any medical diseases with platelet dysfunction Patients with bone marrow diseases and low blood cell production Pregnancy or breast-feeding Smokers

Design outcomes

Primary

MeasureTime frame
Range of motion of the wrist. Timepoint: Before intervention and 3,6 and 12 months after intervention. Method of measurement: Goniometer.;Radiological symptoms. Timepoint: Before intervention and 3,6 and 12 months after intervention. Method of measurement: X-ray and MRI.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPeiman Brouki milan

Iran University of Medical Sciences

brouki.p@iums.ac.ir+98 21 8670 4832

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026