The effects of melatonin on the consumption of opioids

The effects of melatonin on the amount of opioids in orthopedic surgery patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221222056890N2

Enrollment

Registered

2024-06-18

Start date

2024-06-02

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effects of melatonin on the consumption of opioids in orthopedic surgery patients. Adverse effect of other drugs, medicaments and biological substances, initial encounter

Interventions

Intervention group: melanotonin group of patients after surgery, their pain scores will be checked and recorded with VAS scale at 6, 8, 24, 36 and 48 hours after the operation, and the side effects ca

Eligibility

Sex/Gender

All

Age

21 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes, 21 to 60 years old The physical status of the American Society of Anesthesiologists ASA (I and II) is selected for those undergoing orthopedic surgery

Exclusion criteria

Exclusion criteria: Patients with diabetes Heart disease high blood pressure Chronic obstructive respiratory disease Coagulation abnormalities Abnormalities of the spine and patients with opiate dependence and allergy to the studied drugs

Design outcomes

Primary

Measure	Time frame
Pain intensity after surgery using a visual analog scale. Timepoint: After surgery, their pain scores will be checked and recorded at 6, 8, 24, 36 and 48 hours after the operation. Method of measurement: Severity of pain after surgery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahbobeh Rashidi

Ahvaz University of Medical Sciences

rashidi-m@ajums.ac.ir0612222922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026