Investigating the effect of vitamin E in the prevention of kidney dysfunction in infants

Evaluation of the effect of vitamin E in the prevention of acute renal failure in infants weighing more than 1000 admitted to the neonatal intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221220056875N1

Enrollment

150

Registered

2023-04-08

Start date

2023-03-20

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney failure. Acute kidney failure

Interventions

Intervention 1: Intervention group: Vitamin E is prescribed at the dose of 3 units per kilogram of the baby's weight per day. This drug is manufactured by Behsa Company and is given to neonates for 6

Eligibility

Sex/Gender

All

Age

No minimum to 30 Days

Inclusion criteria

Inclusion criteria: Hospitalized in the neonatal intensive care unit Weight more than 1000 grams Not having any congenital or chromosomal abnormalities

Exclusion criteria

Exclusion criteria: Allergy to vitamin E Contraindications for vitamin E use Lack of consent to participate in the study

Design outcomes

Primary

Measure	Time frame
Creatinine. Timepoint: before the treatment and on the second, fourth and sixth days after starting the treatment. Method of measurement: Blood sampling is done from the patients and the creatinine level is determined by a laboratory kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNajmeh Sadat Pishnamazi

Arak University of Medical Sciences

njmpishnamazi@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026