Investigating the effect of magnesum sulfate in reducing the pain of kidney stones

Comparison of the effect of intravenous ketorolac-morphine with intravenous ketorolac-magnesium sulfate on reducing pain in renal colic patients.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221219056870N1

Enrollment

184

Registered

2023-01-18

Start date

2023-01-07

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute renal colic. Calculus of kidney

Interventions

Intervention 1: Intervention group: The acute renal colic patients of this group are prescribed magnesium sulfate with a dose of 2 grams of a 50% solution in a volume of 100cc and at a speed of 15 min

Eligibility

Sex/Gender

All

Age

16 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients older than 16 years Patients with flank or hypogastric pain Patients who have ultrasound based on kidney stones.

Exclusion criteria

Exclusion criteria: Known hypersensitivity to ketorolac and morphine or magnesium sulfate Pregnancy and breastfeeding Any history of opium addiction Breathing rate less than 12 per minute Systolic blood pressure less than 100 mm Hg Unwillingness to participate in the study Inability to understand the concept of VAS Heart or kidney failure Use of painkillers 4 hours before admission

Design outcomes

Primary

Measure	Time frame
Pain reduction of 3 points or more on the VAS scale after drug injection is considered positive. Timepoint: 20, 40 and 60 minutes. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Fallah Bagher SHeidaei

Dezfoul University of Medical Sciences

alighasemlou1374@gmail.com+98 61 4242 9731

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026