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Comparison of the effect of silver nanoparticle dressing spray with chlorhexidine spray on local infection of temporary central venous catheter

A comparative study of the effect of nanoparticle silver dressing spray with chlorhexidine spray local infection of temporary central venous catheters in patients admitted to the special care units of selected Aja hospitals in Tehran A three-blind clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221218056848N1
Enrollment
23
Registered
2024-04-12
Start date
2024-02-08
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Venous Catheter Local Infection. Other specified local infections of the skin and subcutaneous tissue

Interventions

Intervention 1: This research will be 3 groups. 2 intervention groups and a control group. The first intervention group: silver spray will be used for this group. Silver spray will be used in the cent

Sponsors

Artesh University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) having a temporary subclavian or jugular central vein catheter 2) GCS criteria greater than 12) 3) age over 18 years 4) hospitalization of the patient in the ward for at least three days 5) absence of a known immunodeficiency disease 6) No local antibiotic use at the catheter insertion site 7) No local infection at the first dressing change 8) No spray sensitivity in the forearm test (redness and itching) 9) Catheters that are less than 14 days after placement 10) Informed consent and willingness to participate in the study

Exclusion criteria

Exclusion criteria: 1) Death or transfer to another hospital or ward 2) The impossibility of using the spray for any reason 3) removal of the catheter for any reason 4) Refusal to continue participating in the research 5) Taking local medicines in the area

Design outcomes

Primary

MeasureTime frame
Central Catheter Local Infection. Timepoint: One Step a day for 7 days. Method of measurement: Observation Checklist of Local Infection.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Nooriyan

Artesh University of Medical Sciences

mahdinooriyan1991@gmail.com+98 21 4382 4055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026