The effect of Noshin Shahd herbal syrup on the glycemic index of patients with type 2 diabetes

Efficacy of a traditional anti-diabetic herbal composition on glycemic, inflammatory, and oxidative stress parameters in patients with type 2 diabetes. A double-blind randomized clinical trial study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221216056833N2

Enrollment

Registered

2023-12-29

Start date

2024-04-15

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes. Type 2 diabetes mellitus with multiple complications

Interventions

Intervention 1: Intervention group: All the volunteers who meet the entry criteria were directed to the laboratory so that biochemical tests can be performed on them before taking the drug. Volunteers

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 20 and 65 years Consistency of diet and exercise program Body mass index less than 35 HbA1c more than 6.5 Not receiving insulin The patient should take standard medicine except insulin

Exclusion criteria

Exclusion criteria: Performing CABG surgery, occurrence of ASC, heart and brain stroke, pulmonary embolism, deep vein thrombosis or TIA in the last 1 year Taking anti-inflammatory drugs such as aspirin with an anti-inflammatory dose, antioxidant supplements, vitamins and omega-3 capsules (<1 g/day), and immunosuppressive drugs in the last three months Presence of cancer, liver and thyroid diseases pregnancy Smoking and alcohol consumption

Design outcomes

Primary

Measure	Time frame
HOMA-estimated insulin resistance. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: fasting insulin (mU/mL) × fasting glucose (mg/dL)/405.	—

Secondary

Measure	Time frame
Oxidative stress factors. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Spectrophotometry, Elisa kit.;Inflammatory biomarkers. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Elisa kit, Turbidimetric assay.;Glycemic status. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Biochemistry Autoanalyzer, Column chromatography, Elisa kit.;Hematopoietic status. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: CBC.;Biochemistry factors and lipid profile. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Enzymatic assay.	—

Measure

Time frame

Oxidative stress factors. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Spectrophotometry, Elisa kit.;Inflammatory biomarkers. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Elisa kit, Turbidimetric assay.;Glycemic status. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Biochemistry Autoanalyzer, Column chromatography, Elisa kit.;Hematopoietic status. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: CBC.;Biochemistry factors and lipid profile. Timepoint: Before the intervention and 40 days after the intervention. Method of measurement: Enzymatic assay.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaegheh Bahri

Kerman University of Medical Sciences

faegheh.bahri9797@gmail.com+98 34 3325 7448

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026