Investigating the effect of celecoxib on the treatment of bipolar disorder

Investigating the effectiveness of adding celecoxib to sodium valproate in the treatment of patients with bipolar disorder

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221216056832N1

Enrollment

Registered

2023-02-01

Start date

2022-12-31

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Disorder. Bipolar disorder, current episode manic severe with psychotic features

Interventions

Intervention 1: Intervention group: including 30 people in the group treated with celecoxib 400mg along with sodium valproate 20mg/kg daily for 8 weeks. Intervention 2: Control group: 30 children will

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having bipolar disorder Age above 18 years

Exclusion criteria

Exclusion criteria: History of dementia Existence of serious cardiovascular and kidney disease Consumption of substances except for smoking and caffeine

Design outcomes

Primary

Measure	Time frame
Bipolar affective disorde. Timepoint: 2, 4 and 8 weeks after starting celecoxib. Method of measurement: Young mania questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzan Kheirkhah

Babol University of Medical Sciences

drfarzankh@yahoo.com+98 11 4253 9727

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026