The analgesic efficacy of lidocaine/prilocaine cream during fine-needle aspiration biopsy of thyroid nodules

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221212056796N1

Enrollment

Registered

2023-04-15

Start date

2023-04-21

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid nodules. Nontoxic single thyroid nodule

Interventions

Intervention 1: Intervention group: Lidocaine + prilocaine 5% local anesthetic cream of Tehran Chemical Pharmaceuticals in the amount of 2.5 ml (~2.5 grams) will be used uniformly in a thick layer on

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients who have already done an ultrasound and the presence of thyroid nodules have been confirmed. Patients with a nodule larger than one centimeter

Exclusion criteria

Exclusion criteria: Altered mental state or inability to understand questions History of long-term use of opioids or painkillers Allergy to the drug which is used (Lidocaine/Prilocaine)

Design outcomes

Primary

Measure	Time frame
Numerical rating scale (NRS) will be used to check the pain level. The person rates their pain using a scale of 0 to 10. Zero means no pain and 10 means the worst pain condition. Timepoint: Measuring the pain score after fine needle biopsy of thyroid nodules in patients who used lidocaine/prilocaine cream or placebo 60 minutes before the procedure. Method of measurement: Asking the patient about the pain score from 0, the lowest to 10, the highest level of pain.	—

Measure

Time frame

Numerical rating scale (NRS) will be used to check the pain level. The person rates their pain using a scale of 0 to 10. Zero means no pain and 10 means the worst pain condition. Timepoint: Measuring the pain score after fine needle biopsy of thyroid nodules in patients who used lidocaine/prilocaine cream or placebo 60 minutes before the procedure. Method of measurement: Asking the patient about the pain score from 0, the lowest to 10, the highest level of pain.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSajjad Poursaleh

Arak University of Medical Sciences

s_poursaleh@yahoo.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026