Evaluation of palatal wound healing after free gingival graft surgery due to lack of attached gingiva.
Conditions
Interventions
Intervention 1: Intervention group: Placing a gel containing 10% Nano-Emodin for 5 minutes on the wound surface. Intervention 2: Intervention group: Placing a gel containing 10% Nano-Emodin for 5 minu
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients age = 18 years. systemically healthy. The graft dimensions were taken with a maximum width of ten millimeters and a length of fifteen to twenty-five millimeters. Patients should sign the informed consent form to participate in the study after receiving sufficient information about the risks, advantages and disadvantages.
Exclusion criteria
Exclusion criteria: Active gag reflux. Smoking and alcohol consumption, periodontal diseases, traumatic occlusion systemic diseases considered either as the contra-indications of periodontal surgeries or in contradiction with wound healing process such as diabetes and history of treatment with high dose steroids taking anti-coagulation medications, radiotherapy or other types of therapies suppressing the immunity system, pregnancy, breast-feeding, digestive disorders. a history of taking medications distorting the wound healing process or inducing gingival enlargement. the patients missing the follow-up sessions after the surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical effect of photodynamic therapy using Nano-Emodin on the palatal wound healing after free gingival graft surgery. Timepoint: Comparison of the average area of the remaining wound in the palate at intervals of 7, 14, 21 and 28 days after surgery. Comparison of the amount of bleeding after surgery in the first 7 days. Comparison of the degree of color matching and epithelialization in the time interval 7, 14, 21, 28. Comparison of the average index of pain and discomfort in the first 10 days after surgery. Method of measurement: The average area of the remaining wound in the area by image j program. Comparison of the amount of bleeding through a questionnaire. Comparison of color matching with Adobe Photoshop software. Examining the amount of epithelialization through 3% hydrogen peroxide. Index of pain and discomfort using Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Isaabadi
Tehran University of Medical Sciences
Outcome results
None listed