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Evaluation the effect of vitamin D3 in improvement clinical parameters of patients with chronic periodontitis-clinical trial

Evaluation the effect of vitamin D3 in improvement clinical parameters of patients with chronic periodontitis-clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221212056786N3
Enrollment
32
Registered
2023-11-05
Start date
2023-12-11
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: The ingredient used is vitamin D3 4000 soft gel in yellow color. Two 4000 IU vitamin D3 oral supplement capsules (Dana Pharmaceutical Company product) daily, one in

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 45 Years

Inclusion criteria

Inclusion criteria: female Has at least 20 teeth Blood vitamin D levels below 30 ng/ml (normal level is = 30 ng/ml). Healthy Between 30 and 45 years

Exclusion criteria

Exclusion criteria: Recent antibiotic therapy Taking vitamin D supplements Use of corticosteroids or immunosuppressive drugs Taking aspirin tablets NSAID use Taking bisphosphonates or hormone therapy Patients who were in menopause or pregnancy Bone diseases Patient with history of infective endocarditis, congenital problem or acquired heart defects Immunodeficiency History of diabetes Calcium deficiency Other systemic conditions that may affect the periodontium and the treatment protocol

Design outcomes

Primary

MeasureTime frame
Clinical attachment loss. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.

Secondary

MeasureTime frame
Probing depth. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.;Bleeding on probing. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmina zamani

Yazd University of Medical Sciences

miina.zmn99@gmail.com+98 35 3621 2222

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026