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The effect of rifaximin in IBS

Investigating the effect of rifaximin tablets on the quality of life and symptoms of irritable bowel syndrome in patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221211056775N1
Enrollment
60
Registered
2022-12-18
Start date
2023-01-10
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group: 30 patients fill out the questionnaire related to the quality of life of irritable bowel syndrome 2 weeks before starting to take rifaximin tablets and record the s

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Normal body mass index (18-25) Absence of any organic intestinal disease (diagnosis based on colonoscopy in the last 5 years) and absence of any intestinal infection (diagnosis based on stool culture) Absence of any major intestinal surgery Not taking laxatives or antidiarrheal drugs regularly Lack of medical history of gastrointestinal and colorectal diseases and absorption Lack of regular use of antibiotics and corticosteroids and immunosuppressive drugs Not taking drugs that increase bleeding from intestinal mucus such as aspirin, warfarin Absence of severe mental and behavioral disorder Not being pregnant or breastfeeding, being an athlete or being hospitalized Not taking non-steroidal anti-inflammatory drugs Absence of breast cancer in the person herself or first degree relatives

Exclusion criteria

Exclusion criteria: Taking rifaximin tablets from one year before entering the study and changing the diet during the study Failure to continue the study due to drug side effects Reluctance to cooperate Pregnancy during study

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: Two weeks before and two weeks after the intervention. Method of measurement: Specific quality of life questionnaire for patients with irritable bowel syndrome (IBS_QOL).;Clinical symptoms. Timepoint: Two weeks before and two weeks after the intervention. Method of measurement: Clinical interview.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYasin Aziminezhad

Arak University of Medical Sciences

yassazzim74@gmail.com+98 86 3367 3552

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026