Oral mucositis. ????? ??
Conditions
Interventions
Intervention 1: Intervention group: the group receiving common treatments to prevent mucositis plus receiving a daily puff of saffron, which is equivalent to 100 milligrams of saffron with a concentra
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: People's satisfaction with the trial Patients with head and neck cancers undergoing radiotherapy Have received at least 36-40 Gy of radiation At least 4 weeks have passed since the start of their radiotherapy treatment. Not allergic to saffron Absence of heart diseases and blood pressure
Exclusion criteria
Exclusion criteria: Suffering from other oral and dental diseases. Long-term use of anti-coagulant and anti-platelet drugs. Systemic conditions such as pregnancy and breastfeeding, diabetes, hypertension, autoimmune diseases, GVHD, use of saliva reducing drugs, alcohol use, drug addiction, bone marrow transplantation, active lesion, oral infection and mucosal wounds before starting radiotherapy Lack of consent to continue the trial and lack of consent to continue the treatment. Performing any surgery and trauma Suffering from any heart, liver and kidney failure and any disease that has manifestations similar to oral mucositis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral mucositis score. Timepoint: Start time, day 7?14?21?28. Method of measurement: WHO definition of oral mucositis grading: 0_none 1_pain and redness 2_redness, wound, ability to eat solid foods 3_wound, need for liquid diet 4_feeding impossible.;Pain sevirity. Timepoint: Start time, day 7?14?21?28. Method of measurement: Pain Visual analogue scale.;Teeth color. Timepoint: Starting day and day 28. Method of measurement: Vita shade guide. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Zahra Shafiee
Ghoum University of Medical Sciences
Outcome results
None listed