Ischemic stroke. Cerebral infarction
Conditions
Interventions
Intervention 1: Intervention group: 41 patients with a diagnosis of stroke in the first 24 hours of hospitalization entered the study and will receive 3 vials of L-carnitine 1000 mg per day, prepared
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosing and confirming the occurrence of ischemic stroke through clinical and neurological examinations by a neurologist and brain imaging (CT-Scan or MRI) Be over 18 years old. Body mass index be more than 18.5. Having an NIHSS score of greater than 10 and less than 22. The onset of symptoms be less than 24 hours. Having focal neurologic deficit Insensitivity to L-carnitine supplement No history of previous stroke, craniotomy, and other CNS diseases such as seizures, epilepsy, brain tumor, severe brain injury, multiple sclerosis, Alzheimer's, Parkinson's, etc. Not taking antioxidant or anti-inflammatory supplements or multivitamins in the last three months Not suffering from chronic or acute liver and kidney disorders (kidney failure and dialysis)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale (NIHSS) score. Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: The scoring checklist is completed through clinical examinations by a specialist.;Modified Rankin Scale (mRs) score. Timepoint: Before the intervention, on the seventh day of the intervention and three months after the intervention. Method of measurement: The scoring checklist is completed through clinical examinations by a specialist.;Temporal muscle thickness (TMT). Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: Using ultrasound images.;C-reactive protein (CRP). Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: blood test.;Total Antioxidant Capacity (TAC). Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: blood test.;Malondialdehyde (MDA). Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: blood test.;Pro-oxidant Antioxidant Balance (PAB). Timepoint: Before the intervention and on the seventh day of the intervention. Method of measurement: blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamaneh Hajjarzadeh
Ahvaz University of Medical Sciences
Outcome results
None listed