Condition 1: Nasal polyps. Condition 2: Chronic rhino sinusitis. Polyp of nasal cavity Chronic sinusitis, unspecified
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, tacrolimus 0.03% topical drops are prescribed. These drugs are continued daily until the end of the study (9 months). Patients who are tr
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients referred to Shafa Kerman Hospital in 1401 who are candidates for surgery due to chronic rhinosinusitis with polyps (patients who have not responded to common treatments including broad-spectrum antibiotics, inhaled steroids, and short-term courses of oral steroids) Informed consent to enter the study
Exclusion criteria
Exclusion criteria: Age less than 18 years Suffering from genetic diseases including Ciliary Dyskinesia or Cystic Fibrosis Recurrence of polyps less than 3 months after surgery Patients who were in the intervention group and showed sensitivity to tacrolimus drops. Patients who did not refer for follow-up Lack of informed consent to enter the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lund-Kennedy Score. Timepoint: Patients of both groups were followed up at intervals of 3 months, 6 months, and 9 months after surgery, and the Lund-Kennedy score was calculated during endoscopic examination. Method of measurement: Method of measurement: endoscopy and unit of measurement: score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lund-Mckay score. Timepoint: Patients of both groups underwent follow-up at intervals of 3 months, 6 months, and 9 months after surgery. Method of measurement: Method of measurement: CT Scan and unit of measurement: score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Jalali
Kerman University of Medical Sciences
Outcome results
None listed