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Inhaling Sour Lemon Essential Essence and Level of Consciousness

Comparison of the Effectiveness of Inhaling Sour Lemon Essential Essence and Placebo on the Level of Consciousness in Adult Patients with Mild to Moderate Decreased Level of Consciousness

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221203056699N1
Enrollment
68
Registered
2022-12-31
Start date
2022-12-21
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decrease Level of Consciousness. Disorder of central nervous system, unspecified

Interventions

Intervention 1: intervention will be done within 5 days
3 times a day and 20 minutes each time (in order to compensate for limitation of the hospitalization time, the frequency of the intervention has been increased to three times). In this regard, for the
3 times a day and 20 minutes each time, for the control group, by the researcher, cotton soaked with 5 drops of normal saline (as a placebo) was placed in a porous box at a distance of 20-40 cm from t

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with decreased level of consciousness , that at least one week has passed sinse their injury or brain damage. 18 years old and older age Mild to Moderate level of consciousness disorder (GCS 9-14) due to Head Trauma, Neurological Diseases and Stroke. Informed consent of the patient or her/his first degree relatives to participate in the study.

Exclusion criteria

Exclusion criteria: Patients with decreased level of consciousness, as a result of receiving sedatives. Patients with limb paralysis such as Spinal Cord Lesions, due to movement disorders. Intubated or tracheostomy patients. Respiratory allergies or allergies to plant extracts. Problems related to smell and nose injury. Participating in previous studies receiving Complementary and Alternative Medicine interventions from one week before our intervention.

Design outcomes

Primary

MeasureTime frame
Level of Consciousness. Timepoint: The level of consciousness will be measured at the beginning of the study (before the start of the intervention) and every first 5 days, as well as on the eighth day (three days after the last day of the intervention), half an hour before each intervention and 10 minutes after each intervention. Method of measurement: Glasgow coma score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ranjbar

Shiraz University of Medical Sciences

zahra_ranjbar@sums.ac.ir+98 71 3647 4254

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026