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Investigating the effect of the combination of a cardiovascular drug and an anesthetic drug on the amount of bleeding during nose surgery

The effect of medication including dexmedetomidine + remifentanil VS remifentanil on bleeding during rhinoplasty surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221202056688N1
Enrollment
70
Registered
2022-12-17
Start date
2023-02-04
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The amount of bleeding during rhinoplasty surgery. Follow-up care involving plastic surgery of head and neck

Interventions

Intervention 1: Intervention group: receiving dexmedetomidine with a loading dose of 1.0-0.5 µg/kg and a maintenance dose (0.5-0.3 µg/kg/h) and remifentanil with a maintenance dose (0.5-0.25 mcg/kg/mi

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Rhinoplasty surgery candidate No history of nose surgery Not suffering from chronic and severe diseases (diabetes, high blood pressure, cancer, etc.) patients with physical class higher than 2

Exclusion criteria

Exclusion criteria: Patients with systolic blood pressure less than 100 mm Hg Heart rate less than 60 per minute Patients with relative or absolute prohibition of general anesthesia Patients with chronic drug or alcohol use Specific use of any interfering drug during anesthesia

Design outcomes

Primary

MeasureTime frame
Bleeding volume. Timepoint: After the operation is completed. Method of measurement: Calculating the amount of blood in the suction, sterile gases and the surgeon's satisfaction with the surgical field.;Blood pressure. Timepoint: Before the operation, 15-30-45 minutes after the start of the intervention and the end of the operation. Method of measurement: By monitoring the patient's vital signs.;Heart rate. Timepoint: Before the operation, 15-30-45 minutes after the start of the intervention and the end of the operation. Method of measurement: By monitoring the patient's vital signs.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Rahmani

Kerman University of Medical Sciences

elnaz_rahmani26@yahoo.com+98 34 3285 0395

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026