Osteoporosis. Age-related osteoporosis without current pathological fracture
Conditions
Interventions
Intervention 1: Intervention group: Pulse Electro Magnetic field. Intervention 2: Intervention group: Exercise therapy. Intervention 3: Intervention group: Pulsed Electromagnetic field+Exercise therap
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
55 Years to 68 Years
Inclusion criteria
Inclusion criteria: women at the age of 55-68, having reached menopause at least 5 year before the study. A body mass index of 22-30 T-score for the hip or lumbar spine -2.5 SD or less. do not have a history of overioectomy syrgery Do not have a history of osteoporosis fracture
Exclusion criteria
Exclusion criteria: Participating in sports regularly for at least one year before starting the study (regular exercise means at least 30 minutes a day and 3 days a week) Taking drugs that affect bone metabolism, except for daily calcium and vitamin D and weekly alendronite tablets, which will be prescribed by the rheumatology consultant of the study with the same dose for all participants. The presence of any medical problem affecting the person's movement (diabetes - diseases of the vestibular system - uncorrected vision or hearing disorders - neurological diseases A history of surgery in the spine and pelvis and the use of tools to fix it or a history of surgery in the lower limbs • History of hormone therapy in the last 6 months A history of having cardiovascular diseases, such as uncontrolled blood pressure, which will be considered as an exclusion criterion for groups that will do exercise therapy Using physiotherapy modalities effective on bone metabolism, such as using WBV, LPL, PEMF modalities in the last 6 month Using tranquilizers (Tranquillizer) in both minor classifications (anti-anxiety, diazepam, oxazepam, alprazolam, etc.) and major (antipsychotic drugs such as haloperidol, phenotazines, fluphenazine, etc.) in three last month Unwillingness of the samples to continue the treatment and not participating regularly in the treatment program A change in sample conditions that would result in missing one of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral Density. Timepoint: At the beginning of the intervention and 12 weeks after the end of the intervention. Method of measurement: The use of X-Ray absorption method with dual energy DXA will be measured using the HOLOGENIC QDR1000 devic.;Bone Turnover markers-bone specific alkalin phosphatase(BSALP). Timepoint: Before the start of the intervention - immediately after the end of the intervention - after a 12-week follow-up from the end of the intervention. Method of measurement: Blood test and examination of blood sample with the laboratory method of ELISA.;Bone Turnover markers-N- terminal telopeptide of type 1 collagen. Timepoint: Before the start of the intervention - immediately after the end of the intervention - after a 12-week follow-up from the end of the intervention. Method of measurement: Blood test and examination of blood sample with the laboratory method of ELISA.;Quality of life. Timepoint: Before the start of the intervention - immediately after the end of the intervention - after a 12-week follow-up from the end of the intervention. Method of measurement: Quality Of Life Questionnaire Of European Foundation for Osteoporosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Thoracic kyphosis. Timepoint: before and after the intervention (12 weeks later) ,and 12 weeks follow up after the end of the intervention. Method of measurement: Photogrammetry method.;Lumbar lordosis. Timepoint: before and after the intervention (12 weeks later) ,and 12 weeks follow up after the end of the intervention. Method of measurement: Photogrammetry method.;Functional Balance. Timepoint: before and after the intervention (12 weeks later) ,and 12 weeks follow up after the end of the intervention. Method of measurement: Functional balance study with Timed Up and Go (TUG), Unilateral Stance Test(USL).;Muscle Strenght. Timepoint: before and after the intervention (12 weeks later) ,and 12 weeks follow up after the end of the intervention. Method of measurement: Using micro manual muscle tester.;Fear of falling. Timepoint: before and after the intervention (12 weeks later) ,and 12 weeks follow up after the end of the intervention. Method of measurement: persian version of Falls Efficacy Scale-International Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh Shadmehr
Tehran University of Medical Sciences
Outcome results
None listed